Review: Comparing drug treatments in epilepsy
نویسندگان
چکیده
منابع مشابه
New drug treatments for epilepsy
After the introduction of valproate in 1973, excluding benzodiazepines, there was a 19 year gap before the introduction of vigabatrin, the first in a series of new antiepileptic drugs to be developed and licensed. At the time of writing gabapentin, lamotrigine, oxcarbazepine, tiagabine, and topiramate have a licence in the United Kingdom. Zonisamide and levetiracetam are licensed in some countr...
متن کاملDrug Discovery in Epilepsy: A Synthetic Review
Although recurrent unprovoked seizures or epilepsy has been known for more than three thousand years, and even considering pivotal contributions like that of Hypocrates (circa 400 BC) establishing epilepsy as a brain disease instead of a religious or evil phenomenon, it was not until the 20th century that the first relatively effective antiepileptic drugs were discovered. Starting from phenobar...
متن کاملPost-Traumatic, Drug-Resistant Epilepsy and Review of Seizure Control Outcomes from Blinded, Randomized Controlled Trials of Brain Stimulation Treatments for Drug-Resistant Epilepsy
BACKGROUND Many post-traumatic epilepsy (PTE) patients become resistant to medications. Nervous stimulation as a treatment for drug-resistant epilepsy (DRE) is an active area of clinical investigation. OBJECTIVE To summarize methods, reported seizure control outcome measures, and adverse events from blinded, randomized control trials (RCTs) for selected invasive brain stimulation (IBS) and no...
متن کاملCCL2 Polymorphism in Drug-Resistant and Drug-Responsive Patients with Epilepsy in Isfahan, Iran
ABSTRACT Background and objective: Approximately 50 million people worldwide (1% of the world's population) suffer from epilepsy. Among 700 thousand people with epilepsy in Iran, 20% have refractory epilepsy. Accumulation of leukocytes in patients' brain parenchyma is thought to be related to different types of epilepsy. Recent clinical observat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Therapeutic Advances in Neurological Disorders
سال: 2009
ISSN: 1756-2864,1756-2864
DOI: 10.1177/1756285609102327